ea0038p192 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2015
Yiannakas Adonis
, McNeilly Alison D
, Gallagher Jennifer
, Wright Kathryn
, McCrimmmon Rory J
Obesity and the metabolic syndrome are chronic inflammatory states that are now understood to be involved in the development type 2 Diabetes. Hypothalamic cytokine signalling is thought to influence neuroendocrine networks critical to the dynamic maintenance of glucose homeostasis. Interleukin 6 (IL6) is a cytokine that displays tissue-specificity and is instrumental in the mounting of the acute phase response, as well as in the subsequent resolving and adaptive phase. IL6 is ...